Preheat Oven: Preheat your oven to 375°F (190°C) and line a baking sheet with aluminum foil or parchment paper for easy cleanup.
Season Wings: Pat the chicken wings dry with paper towels. Season with salt and pepper and arrange them in a single layer on the baking sheet.
Initial Bake: Bake the wings for 25 minutes, then flip and continue baking for another 20 minutes until they are nearly fully cooked and slightly crispy.
Make the Sauce: While the wings are baking, mix the barbecue sauce, honey, soy sauce, apple cider vinegar, garlic powder, onion powder, smoked paprika, and red chili flakes in a bowl.
Coat the Wings: Remove the wings from the oven and increase the temperature to 425°F (220°C). Toss the wings in the sauce mixture until evenly coated.
Final Bake: Return the coated wings to the baking sheet and bake for an additional 10-15 minutes, or until the sauce is bubbly and caramelized.
Garnish and Serve: Sprinkle with chopped cilantro and sesame seeds before serving.